Integrin alpha4beta1

Integrin alpha4beta1 is a FIBRONECTIN and VCAM-1 receptor present on LYMPHOCYTES; MONOCYTES; EOSINOPHILS; NK CELLS and thymocytes. It is involved in both cell-cell and cell- EXTRACELLULAR MATRIX adhesion and plays a role in INFLAMMATION, hematopoietic cell homing and immune function, and has been implicated in skeletal MYOGENESIS; NEURAL CREST migration and proliferation, lymphocyte maturation and morphogenesis of the PLACENTA and HEART.

Also Known As:

VLA-4; CD49d-CD29; Integrin Heterodimer alpha4beta1; Integrin alpha(4)beta(1); Very Late Activation Antigen-4; Very Late Antigen-4; alpha4beta1 Integrin; Antigen-4, Very Late; Heterodimer alpha4beta1, Integrin; Integrin, alpha4beta1; Late Antigen-4, Very; Very Late Activation Antigen 4; Very Late Antigen 4; alpha4beta1, Integrin; alpha4beta1, Integrin Heterodimer

Carbohydrates: 22516
- Glycoconjugates: 1370
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - Cell Adhesion Molecules: 4912
        Lymphocyte Homing Receptors: 25
        Integrin alpha4beta1: 565
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - Cell Adhesion Molecules: 4912
        Lymphocyte Homing Receptors: 25
        Integrin alpha4beta1: 565
  - Membrane Proteins: 10262
    - Membrane Glycoproteins: 2277
      - Cell Adhesion Molecules: 4912
        Lymphocyte Homing Receptors: 25
        Integrin alpha4beta1: 565
    - Cell Surface Receptors: 2156
      - Immunologic Receptors: 10
        Integrins: 14566
        Fibronectin Receptors: 37
        Integrin alpha4beta1: 565
        Very Late Antigen Receptors: 8
        Integrin alpha4beta1: 565
        Lymphocyte Homing Receptors: 25
        Integrin alpha4beta1: 565
Biological Factors: 2560
- Antigens: 145631
  - Surface Antigens: 5857
    - Cell Adhesion Molecules: 4912
      - Lymphocyte Homing Receptors: 25
        Integrin alpha4beta1: 565

Yi Hsing Chen Selected Research

Yi Hsing Chen Research Topics

Disease

Drug/Important Bio-Agent (IBA)